OncologyMerck

Merck Reports Phase 2 Results for Vibostolimab Plus Keytruda in Advanced Melanoma

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Biotechnology Media Insights

Editorial Team · June 5, 2025

Merck announces Phase 2 KEYVIBE-001 trial results showing vibostolimab coformulated with pembrolizumab demonstrates activity in advanced melanoma.

Oncology cancer research laboratory with microscope and cell samples

Merck today announced Phase 2 results from the KEYVIBE-001 trial evaluating MK-7684A, a coformulation of vibostolimab (anti-TIGIT) and pembrolizumab (Keytruda), in patients with advanced melanoma. The trial demonstrated an objective response rate of 43% in PD-L1-positive patients who had not received prior anti-PD-1 therapy.

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