OncologyJohnson & Johnson

Johnson & Johnson Reports Positive PAPILLON Trial Results for Amivantamab in Lung Cancer

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Biotechnology Media Insights

Editorial Team · June 12, 2025

J&J announces positive Phase 3 PAPILLON trial results showing amivantamab plus chemotherapy improves outcomes in EGFR exon 20 insertion-mutated NSCLC.

Oncology cancer research laboratory with microscope and cell samples

Johnson & Johnson today announced positive results from the Phase 3 PAPILLON trial evaluating amivantamab plus carboplatin-pemetrexed chemotherapy in patients with EGFR exon 20 insertion-mutated non-small cell lung cancer. The trial met its primary endpoint, demonstrating a significant improvement in progression-free survival compared to chemotherapy alone.

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