Bristol Myers Squibb Reports Four-Year CheckMate-649 Data for Opdivo in Gastric Cancer
Biotechnology Media Insights
Editorial Team · February 10, 2025
BMS presents four-year overall survival data from CheckMate-649 trial showing durable benefit of Opdivo plus chemotherapy in gastric cancer.

Bristol Myers Squibb today presented four-year overall survival data from the Phase 3 CheckMate-649 trial evaluating Opdivo (nivolumab) plus chemotherapy in patients with previously untreated advanced gastric, gastroesophageal junction, or esophageal adenocarcinoma. The data showed that the overall survival benefit of Opdivo was maintained at four years, with 15% of patients in the Opdivo arm alive at four years compared to 7% in the chemotherapy arm.
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