OncologyAstraZeneca

AstraZeneca Reports Phase 3 Results for Savolitinib in MET Exon 14-Mutated NSCLC

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Biotechnology Media Insights

Editorial Team · September 15, 2025

AstraZeneca announces Phase 3 SAFFRON trial results evaluating savolitinib in patients with MET exon 14 skipping mutation-positive non-small cell lung cancer.

Oncology cancer research laboratory with microscope and cell samples

AstraZeneca today announced results from the Phase 3 SAFFRON trial evaluating savolitinib in patients with MET exon 14 skipping mutation-positive non-small cell lung cancer (NSCLC). The trial demonstrated significant improvements in objective response rate and progression-free survival compared to docetaxel in previously treated patients.

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