OncologyAstraZeneca
AstraZeneca Reports Phase 3 Results for Savolitinib in MET Exon 14-Mutated NSCLC
BMI
Biotechnology Media Insights
Editorial Team · September 15, 2025
AstraZeneca announces Phase 3 SAFFRON trial results evaluating savolitinib in patients with MET exon 14 skipping mutation-positive non-small cell lung cancer.

AstraZeneca today announced results from the Phase 3 SAFFRON trial evaluating savolitinib in patients with MET exon 14 skipping mutation-positive non-small cell lung cancer (NSCLC). The trial demonstrated significant improvements in objective response rate and progression-free survival compared to docetaxel in previously treated patients.
BMI
Biotechnology Media Insights
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