OncologyAstraZeneca

AstraZeneca Reports Five-Year PROfound Data for Lynparza in BRCA-Mutated Prostate Cancer

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Biotechnology Media Insights

Editorial Team · January 28, 2024

AstraZeneca presents five-year follow-up data from PROfound trial showing durable benefit of Lynparza in BRCA-mutated metastatic CRPC.

Oncology cancer research laboratory

AstraZeneca today presented five-year follow-up data from the Phase 3 PROfound trial evaluating Lynparza (olaparib) versus enzalutamide or abiraterone in patients with metastatic castration-resistant prostate cancer with BRCA1/2 or ATM mutations. The data showed that the overall survival benefit of Lynparza was maintained over five years of follow-up.

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