Johnson & Johnson Reports Phase 2 MajesTEC-1 Results for Tecvayli in Multiple Myeloma
Biotechnology Media Insights
Editorial Team · January 30, 2024
J&J announces Phase 2 MajesTEC-1 trial results showing teclistamab achieves high response rates in heavily pretreated relapsed/refractory multiple myeloma.

Johnson & Johnson today announced results from the Phase 2 MajesTEC-1 trial evaluating Tecvayli (teclistamab-cqyv) in patients with relapsed or refractory multiple myeloma who had received at least three prior lines of therapy. The trial demonstrated an overall response rate of 63%, with a complete response rate of 39% in heavily pretreated patients. These results led to FDA accelerated approval of Tecvayli.
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