OncologyEli Lilly

Eli Lilly Reports Positive EMBER-3 Trial Results for Imlunestrant in Breast Cancer

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Biotechnology Media Insights

Editorial Team · July 20, 2025

Eli Lilly announces positive Phase 3 EMBER-3 trial results showing imlunestrant significantly improves progression-free survival in ESR1-mutated breast cancer.

Oncology cancer research laboratory with microscope and cell samples

Eli Lilly today announced positive results from the Phase 3 EMBER-3 trial evaluating imlunestrant in patients with estrogen receptor-positive, HER2-negative advanced breast cancer with ESR1 mutations. The trial met its primary endpoint, demonstrating a significant improvement in progression-free survival compared to standard endocrine therapy in patients with ESR1 mutations.

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