OncologyAstraZeneca

AstraZeneca and Daiichi Sankyo Report Updated DESTINY-Breast06 Data for Enhertu in HER2-Low Breast Cancer

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Biotechnology Media Insights

Editorial Team · July 22, 2025

AstraZeneca and Daiichi Sankyo present updated Phase 3 DESTINY-Breast06 data showing Enhertu significantly improves outcomes in HER2-low and HER2-ultralow breast cancer.

Oncology cancer research laboratory with microscope and cell samples

AstraZeneca and Daiichi Sankyo today presented updated data from the Phase 3 DESTINY-Breast06 trial evaluating Enhertu (trastuzumab deruxtecan) in patients with HER2-low and HER2-ultralow hormone receptor-positive, HER2-negative metastatic breast cancer. The updated data showed a median progression-free survival of 13.2 months with Enhertu compared to 8.1 months with chemotherapy.

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