OncologyAstraZeneca

AstraZeneca Presents Five-Year Data for Calquence in Chronic Lymphocytic Leukemia

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Biotechnology Media Insights

Editorial Team · April 22, 2025

AstraZeneca shares five-year follow-up data from ASCEND trial showing sustained progression-free survival benefit of Calquence in relapsed/refractory CLL.

Oncology cancer research laboratory with microscope and cell samples

AstraZeneca today presented five-year follow-up data from the Phase 3 ASCEND trial evaluating Calquence (acalabrutinib) in patients with relapsed or refractory chronic lymphocytic leukemia (CLL). The data showed that Calquence maintained a significant progression-free survival benefit over investigator's choice of idelalisib plus rituximab or bendamustine plus rituximab at five years.

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