CardiovascularMerck

Merck Reports Positive STELLAR Trial Results for Sotatercept in Pulmonary Arterial Hypertension

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Biotechnology Media Insights

Editorial Team · April 20, 2025

Merck announces positive Phase 3 STELLAR trial results showing sotatercept significantly improves exercise capacity in pulmonary arterial hypertension patients.

Cardiovascular heart disease research with medical imaging and laboratory

Merck today announced positive results from the Phase 3 STELLAR trial evaluating sotatercept in patients with pulmonary arterial hypertension (PAH) on background therapy. The trial met its primary endpoint, demonstrating a significant improvement in six-minute walk distance compared to placebo.

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