OncologyRoche

Roche Reports Positive SKYSCRAPER-08 Trial Results for Tiragolumab in Esophageal Cancer

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Biotechnology Media Insights

Editorial Team · September 1, 2025

Roche announces positive Phase 3 SKYSCRAPER-08 trial results showing tiragolumab plus atezolizumab and chemotherapy improves outcomes in esophageal squamous cell carcinoma.

Oncology cancer research laboratory with microscope and cell samples

Roche today announced positive results from the Phase 3 SKYSCRAPER-08 trial evaluating tiragolumab plus atezolizumab and chemotherapy in patients with previously untreated advanced esophageal squamous cell carcinoma (ESCC). The trial met its co-primary endpoints, demonstrating significant improvements in overall survival and progression-free survival.

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