OncologyRoche
Roche Reports Positive SKYSCRAPER-08 Trial Results for Tiragolumab in Esophageal Cancer
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Biotechnology Media Insights
Editorial Team · September 1, 2025
Roche announces positive Phase 3 SKYSCRAPER-08 trial results showing tiragolumab plus atezolizumab and chemotherapy improves outcomes in esophageal squamous cell carcinoma.

Roche today announced positive results from the Phase 3 SKYSCRAPER-08 trial evaluating tiragolumab plus atezolizumab and chemotherapy in patients with previously untreated advanced esophageal squamous cell carcinoma (ESCC). The trial met its co-primary endpoints, demonstrating significant improvements in overall survival and progression-free survival.
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