RespiratoryRegeneron

Regeneron and Sanofi Present Two-Year BOREAS Data for Itepekimab in COPD

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Biotechnology Media Insights

Editorial Team · October 22, 2025

Regeneron and Sanofi share two-year follow-up data from BOREAS trial showing sustained reduction in COPD exacerbations with itepekimab in former smokers.

Respiratory disease research with pharmaceutical drug development laboratory

Regeneron and Sanofi today presented two-year follow-up data from the Phase 3 BOREAS trial evaluating itepekimab in patients with moderate-to-severe COPD who are former smokers. The data showed that the reduction in annualized COPD exacerbation rates was maintained over two years of treatment, with itepekimab demonstrating a 24% reduction compared to placebo.

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