CardiovascularPfizer

Pfizer Reports Three-Year ATTR-ACT Data for Vyndaqel in Transthyretin Cardiomyopathy

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Biotechnology Media Insights

Editorial Team · October 12, 2025

Pfizer presents three-year follow-up data from ATTR-ACT trial showing sustained cardiovascular benefits of Vyndaqel (tafamidis) in transthyretin cardiomyopathy.

Cardiovascular heart disease research with medical imaging and laboratory

Pfizer today presented three-year follow-up data from the Phase 3 ATTR-ACT trial evaluating Vyndaqel (tafamidis meglumine) and Vyndamax (tafamidis) in patients with transthyretin cardiomyopathy (ATTR-CM). The data showed that the mortality and cardiovascular hospitalization benefits of tafamidis were maintained and potentially enhanced over three years of treatment.

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