CardiovascularMerck
Merck Reports Phase 3 Results for Tafolecimab in Hypercholesterolemia
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Biotechnology Media Insights
Editorial Team · October 15, 2025
Merck announces Phase 3 trial results showing tafolecimab, a PCSK9 inhibitor, significantly reduces LDL cholesterol in patients with hypercholesterolemia.

Merck today announced Phase 3 trial results for tafolecimab, a fully human anti-PCSK9 monoclonal antibody, in patients with hypercholesterolemia. The trials demonstrated significant reductions in LDL cholesterol of approximately 60% compared to placebo when added to statin therapy.
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