OncologyBristol Myers Squibb
Bristol Myers Squibb Reports Positive CheckMate-9DW Results for Opdivo in Liver Cancer
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Biotechnology Media Insights
Editorial Team · September 22, 2025
BMS announces positive Phase 3 CheckMate-9DW trial results showing nivolumab plus ipilimumab improves overall survival in first-line hepatocellular carcinoma.

Bristol Myers Squibb today announced positive results from the Phase 3 CheckMate-9DW trial evaluating nivolumab plus ipilimumab versus sorafenib or lenvatinib in patients with previously untreated unresectable hepatocellular carcinoma (HCC). The combination reduced the risk of death by 21% compared to sorafenib or lenvatinib.
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