NeurologyBiogen

Biogen Reports Phase 3 ATLAS Trial Results for Tofersen in SOD1-ALS

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Biotechnology Media Insights

Editorial Team · June 18, 2025

Biogen announces Phase 3 ATLAS trial results showing tofersen significantly delays onset of ALS symptoms in presymptomatic SOD1 mutation carriers.

Neurology brain research laboratory with advanced imaging equipment

Biogen today announced results from the Phase 3 ATLAS trial evaluating tofersen in presymptomatic individuals with SOD1 mutations who are at high risk of developing ALS. The trial demonstrated that tofersen significantly delayed the onset of ALS symptoms and functional decline compared to placebo.

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