AbbVie Reports Phase 3 MOTIVATE Results for Skyrizi in Crohn's Disease
Biotechnology Media Insights
Editorial Team · September 25, 2024
AbbVie announces Phase 3 MOTIVATE trial results showing risankizumab achieves clinical remission and endoscopic response in biologic-experienced Crohn's disease.

AbbVie today announced results from the Phase 3 MOTIVATE trial evaluating Skyrizi (risankizumab) in patients with moderately to severely active Crohn's disease who had an inadequate response or intolerance to biologic therapy. The trial met its primary endpoints, demonstrating significantly higher rates of clinical remission and endoscopic response compared to placebo at week 12.
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