DermatologyRegeneron

Regeneron and Sanofi Report Phase 3 Results for Dupixent in Pediatric Prurigo Nodularis

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Biotechnology Media Insights

Editorial Team · August 12, 2025

Regeneron and Sanofi announce Phase 3 LIBERTY PN PRIME2 trial results showing Dupixent significantly reduces itch and skin lesions in adolescents with prurigo nodularis.

Dermatology skin treatment research with pharmaceutical laboratory equipment

Regeneron and Sanofi today announced results from the Phase 3 LIBERTY PN PRIME2 trial evaluating Dupixent (dupilumab) in adolescents aged 12 to 17 years with prurigo nodularis. The trial met its primary endpoint, demonstrating significant reductions in itch intensity and skin lesion counts compared to placebo at week 24.

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