CardiovascularNovartis

Novartis Leqvio Demonstrates Sustained LDL Cholesterol Reduction with Twice-Yearly Dosing

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Biotechnology Media Insights

Editorial Team · March 5, 2025

Novartis announces long-term data showing Leqvio (inclisiran) maintains significant LDL-C reductions with just two injections per year in high cardiovascular risk patients.

Cardiovascular heart disease research with medical imaging and laboratory

Novartis today presented long-term data from the ORION clinical program showing that Leqvio (inclisiran) maintains approximately 50% reduction in LDL cholesterol with twice-yearly subcutaneous injections. The data, presented at a major cardiology congress, included patients followed for up to three years.

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