CardiovascularNovartis

Novartis Reports ORION-4 Cardiovascular Outcomes Data for Leqvio

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Biotechnology Media Insights

Editorial Team · July 22, 2024

Novartis presents ORION-4 cardiovascular outcomes trial data showing Leqvio significantly reduces major adverse cardiovascular events in patients with established CVD.

Cardiovascular research laboratory

Novartis today presented data from the ORION-4 cardiovascular outcomes trial evaluating Leqvio (inclisiran) in patients with established cardiovascular disease. The trial demonstrated a significant reduction in major adverse cardiovascular events with Leqvio compared to placebo, confirming that LDL cholesterol reduction with inclisiran translates into cardiovascular event reduction.

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