Infectious DiseaseMerck

Merck Reports Phase 3 MELODY Trial Results for Clesrovimab in RSV Prevention in Infants

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Biotechnology Media Insights

Editorial Team · August 20, 2025

Merck announces Phase 3 MELODY trial results showing clesrovimab significantly reduces RSV-associated lower respiratory tract infections in infants.

Pharmaceutical research laboratory with drug development equipment

Merck today announced results from the Phase 3 MELODY trial evaluating clesrovimab, a monoclonal antibody, for the prevention of respiratory syncytial virus (RSV)-associated lower respiratory tract infections in infants. The trial demonstrated a significant reduction in medically attended RSV-associated lower respiratory tract infections compared to placebo.

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