Infectious DiseaseMerck

Merck and Gilead Report Phase 3 Results for Once-Weekly Oral HIV Treatment Combination

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Biotechnology Media Insights

Editorial Team · July 8, 2025

Merck and Gilead Sciences announce Phase 3 results for once-weekly oral islatravir plus lenacapavir combination showing non-inferior HIV viral suppression.

Pharmaceutical research laboratory with drug development equipment

Merck and Gilead Sciences today announced Phase 3 results from the ILLUMINATE-B trial evaluating once-weekly oral islatravir plus lenacapavir for HIV treatment. The trial demonstrated non-inferiority to daily oral standard-of-care regimens in maintaining HIV viral suppression at 52 weeks.

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