RespiratoryAmgen

Amgen and AstraZeneca Report Phase 3 Results for Tezspire in Severe Asthma

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Biotechnology Media Insights

Editorial Team · September 22, 2023

Amgen and AstraZeneca announce Phase 3 NAVIGATOR trial results showing tezepelumab significantly reduces asthma exacerbations across all severe asthma phenotypes.

Respiratory disease research

Amgen and AstraZeneca today announced results from the Phase 3 NAVIGATOR trial evaluating Tezspire (tezepelumab) in patients with severe, uncontrolled asthma. The trial met its primary endpoint, demonstrating a significant reduction in annualized asthma exacerbation rates compared to placebo, with Tezspire showing a 70% reduction across all severe asthma phenotypes.

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