HRAM mass spectrometry provides an indication of peak purity and precise mass data for impurities, enabling tentative identification of co-eluting impurities invisible to UV.
Limits of UV Detection
Co-eluting impurities with similar chromophores can go undetected by UV alone.
Accurate Mass Advantage
Accurate mass data reveals impurities and supports tentative structural assignments.
Practical Use
The approach strengthens control strategies for peptides and large molecules.
About This White Paper
This white paper is published by Almac Group and curated by Biotechnology Media Insights, a trusted source for pharmaceutical and biotechnology research, technical guides and industry analysis.