NeurologyBiogen

Biogen and Eisai Report Primary CLARITY AD Results for Leqembi in Early Alzheimer's

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Biotechnology Media Insights

Editorial Team · February 5, 2024

Biogen and Eisai announce primary Phase 3 CLARITY AD trial results showing Leqembi significantly slows clinical decline in early Alzheimer's disease.

Neurology brain research laboratory

Biogen and Eisai today announced primary results from the Phase 3 CLARITY AD trial evaluating Leqembi (lecanemab-irmb) in patients with early Alzheimer's disease. The trial met its primary endpoint, demonstrating a significant slowing of clinical decline compared to placebo at 18 months, as measured by the CDR-SB score. Leqembi also significantly reduced amyloid plaques and tau tangles.

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