The Evolving Landscape: Cutting-Edge Approaches for Difficult-to-Deliver Molecules
Resolving solubility and permeability concerns demands new technologies.
Yizheng Cao, Principal Scientist at Serán BioScience, shares insight on challenges in oral drug delivery for complex molecules including PROTACs, peptides and poorly soluble small molecules.
Yizheng Cao, Principal Scientist at Serán BioScience, shares insight on challenges in oral drug delivery for complex molecules including PROTACs, peptides and poorly soluble small molecules.
Solubility and Permeability
Beyond-rule-of-five molecules challenge traditional formulation and call for new delivery strategies.
Enabling Technologies
Amorphous dispersions, lipid systems and particle engineering each address different barriers to absorption.
Early Screening
Screening formulations early identifies the optimal approach before committing to a development path.
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