Pharmaceutical tablet manufacturing and lubrication process in production facility
Drug Formulation

Expanding Your Tablet Lubrication Toolbox: Addressing Common Challenges

Gattefossé USA
Drug Formulation

Safer, more robust alternatives for pharmaceutical tablet manufacturing.

This whitepaper discusses common tablet lubrication challenges and introduces Compritol® 888 ATO as a proven, nitrosamine-free lubricant that influences compression behavior and tablet performance.

This whitepaper discusses common tablet lubrication challenges and introduces Compritol® 888 ATO as a proven, nitrosamine-free lubricant that influences compression behavior and tablet performance.

Common Lubrication Challenges

Over-lubrication can slow dissolution and weaken tablets, while under-lubrication causes sticking and capping.

A Nitrosamine-Free Alternative

Compritol® 888 ATO offers a robust option that supports compression performance and regulatory compliance.

Impact on Tablet Performance

Lubricant choice affects hardness, disintegration and dissolution, so selection should be data-driven.

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